Good News | Magic Health Wins the Very “Oral Beauty” Award at 2024 Very Food Awards

On the evening of November 28, the 2024 Very Food Innovation Award Ceremony, hosted by the Food Research Institute FTA, was grandly held in Hangzhou. 
This ceremony is dedicated to commending the upstream raw materials, end - products, and scientific research and innovation achievements that have made substantial contributions and remarkable accomplishments in the food industry. 
By bringing together global food innovation concepts, presenting cutting - edge raw materials, and focusing on new horizons in the food sector, it endeavors to spark new technologies and ideas through award evaluations and to uncover outstanding raw materials and products.

Maiggic™ PQQ (Pyrroloquinoline Quinone Disodium Salt) by Magic Health emerged victorious from 267 entries and was honored with the Very “Oral Beauty” Award in the Raw Material Category of the Year.

PQQ, also referred to as the “dark horse in anti - aging,” “cutting - edge anti - aging technology,” or “miraculous nutrient,” has been extensively applied in common foods and dietary supplements overseas. 
It has been frequently reported in top - tier academic journals like Nature and Science and has demonstrated outstanding performance in anti - aging and cellular rejuvenation. In recent years, PQQ has gradually come into the domestic public's view. In response to consumers' upgraded and more refined demands for oral beauty products, the combination of PQQ with various star ingredients has triggered a new upsurge in the oral beauty market, helping the skin resist aging, reduce wrinkles, and combat oxidation at the cellular level.

Skin aging can be categorized into extrinsic aging and intrinsic aging. Extrinsic aging is most prominently manifested as photoaging, which is induced by the damage caused by repeated exposure of human skin to ultraviolet (UVA and UVB) radiation. Intrinsic aging, or natural aging, is mainly characterized by aging in non - exposed areas due to internal factors. These include aging related to age, physiological aging, a decline in the synthesis capacity of collagen and elastin in the skin, and a decrease in the fluidity of the cytoplasm and extracellular matrix.

Numerous studies have revealed that PQQ has a remarkable effect on improving skin aging. The results of an experiment on human fibroblasts showed that when a cellular photoaging model was constructed by irradiating with UVA, PQQ could down - regulate the expression of β - galactosidase from 78.24% to 51.30% and simultaneously down - regulate the expression of senescence - marker genes matrix metalloproteinases mmp1 and mmp3 [1]. 
Similarly, another study of the same model type indicated that PQQ has a protective effect against UVA - induced HDF aging, which may be associated with the anti - apoptotic SIRT1/Nrf2/HO - 1 pathway and SIRT6 signaling [2]. 
Additionally, some research has found that when constructing a cellular photoaging model by irradiating human fibroblasts with UVB, PQQ can regulate the gene expression of COL - Ⅰ and COL - Ⅲ, inhibit collagen degradation, and promote collagen production, thus exerting a photoprotective effect [3].

The path of innovation is boundless. Magic Health is actively promoting the regulatory registration of core raw materials in the domestic and international food and cosmetics industries. Moreover, it will continue to enhance product quality research, efficacy research, and application research, constantly providing customers with high - quality products and personalized health solutions, and continuously injecting new vitality into the future development of the food industry.

References:
[1] Zhang Chunli, Zou Yang, Lin Jinde, et al. Protective effect and mechanism of pyrroloquinoline quinone on UVA - induced senescence of human dermal fibroblasts[J]. Acta Universitatis Medicinalis Nanjing (Natural Science Edition), 2013, 33(03): 337 - 341.
[2] Zhang C, Wen C, Lin J, Shen G. Protective effect of pyrroloquinoline quinine on ultraviolet A irradiation - induced human dermal fibroblast senescence in vitro proceeds via the anti - apoptotic sirtuin 1/nuclear factor - derived erythroid 2 - related factor 2/heme oxygenase 1 pathway. Mol Med Rep. 2015 Sep;12(3):4382 - 4388.
[3] Wang Jing, Shi Zhinan, Gu Li, et al. Inhibitory effect of pyrroloquinoline quinone on premature senescence of human dermal fibroblasts induced by UVB[J]. Journal of Nantong University (Medical Sciences), 2023, 43(3): 224 - 229.