Ergothioneine (EGT)
Overview
Product Details
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Feature
Product Function
Anti-lnflammatory
The Inhibitory Effects of the Extract of Chrysanthemum Chrysalis on the Formation of 8-BrdG
Experiments have shown that ergothioneine can significantly inhibit the occurrence of inflammation. in theergothioneine experimental group, the inflammatory factor markers 8-bromoriboseguanine (8-BrdG) andmyeloperoxidase(APO)were significantly reduce.
(T.Asahi. et al.2016)
Protect Skincell DNA
TUNEL: TUNEL can mark DNA fragments, so the greater the fluorescence intensity, the more damaged DNA；
DAPl: DAPl can bind double-helix DNA, so the greater the fluorescence intensity, the more complete double-helx DNA；
Compared with the UVA group, the TUNEL fluorescence intensity in the ergothioneine+UVA group was smaller, and theDAPl fluorescence intensity was greater, indicating that ergothioneine can protect DNA from UVA damage
(Youcheng Hseu, et al. 2015)
Ergothioneine's Mechanism of Action
EGT is an antioxidant component with a clear mechanism of entry into themitochondria and nucleus via the transporter protein OCTN1(ETT).It scavenges freeradicals and activates the endogenous antioxidant system through the Nrf2 pathway,promoting the generation of endogenous antioxidants
Experimental data
Stability test
lack of information
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